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Transferrin Receptor Monoclonal Antibody (H68.4), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen 136800

Product Code. 10372703

  • 492.00 EUR / Each

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Description

Description

H68.4 is specific to residues 3-28 of the human transferrin receptor (TfR) tail.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
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Lot Number Certificate Type Date Catalog Number
Lot NumberAB404440 Certificate TypeCertificate of Analysis Date05/02/2025 Catalog Number
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Transferrin Receptor Monoclonal Antibody (H68.4), Invitrogen™ > 100 μg; Unconjugated

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