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Thermo Scientific Chemicals U0126, ≥99%
Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2
177.00 EUR - 667.00 EUR
Chemical Identifiers
| CAS | 109511-58-2 |
|---|---|
| Molecular Formula | C18H16N6S2, C18H16N6S2 |
| Synonym | 1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15423859
|
Thermo Scientific Chemicals
J61246.MC |
100 mg |
340.00 EUR
100mg |
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|
15413859
|
Thermo Scientific Chemicals
J61246.MB |
25 mg |
177.00 EUR
25mg |
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|
15403859
|
Thermo Scientific Chemicals
J61246.|H |
300 mg | |||||||
Description
U0126, is used as a selective MAP Kinase Kinase (MKK, MEK) inhibitor. U-0126 has been observed to inhibit promoters containing an AP-1 response element, while in contrast having no effect on promoters that lack an AP-1 response group. U-0126 is also useful in neuronal studies in mice since it displays inhibitory effects against oxidative stress. U-0126 is an activator of PGC-1, mtTFA and nuclear respiratory factor.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Chemical Identifiers
| 109511-58-2 | |
| C18H16N6S2, C18H16N6S2 | |
| 1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene |
Specifications
| White | |
| Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2 | |
| C18H16N6S2, C18H16N6S2 | |
| 1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene | |
| Signal Transduction Reagent | |
| DVEXZJFMOKTQEZ-JYFOCSDGSA-N | |
| (2Z,3Z)-bis({amino[(2-aminophenyl)sulfanyl]methylidene})butanedinitrile | |
| ≥99% |
| -30°C to -10°C | |
| 109511-58-2 | |
| 380.49g/mol | |
| Soluble in DMSO; Poorly soluble in ethanol and water | |
| Powder | |
| N\C(SC1=CC=CC=C1N)=C(\C#N)/C(/C#N)=C(\N)SC1=CC=CC=C1N | |
| 380.49 |
Safety and Handling
Recommended Storage : Store at -20°C
RUO – Research Use Only