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Thermo Scientific Chemicals Z-Val-Val-Nle Diazomethyl Ketone

Product Code. 15436449
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Quantity:
50 mg
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This item is not returnable. View return policy

Description

 

Z-Val-Val-Nle diazomethyl ketone is used as an irreversible cathepsin inhibitor that is 380 times more effective in inactivating cathepsin S than L. It is often abbreviated as DMK. Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Specifications

Quantity 50 mg
Description White to Off-white
Content And Storage -30°C to -10°C
For Use With (Application) Inactivates thiol proteinases; an irreversible cathepsin inhibitor
CAS 155026-49-6
Molecular Formula C25H37N5O5, C25H37N5O5
Formula Weight 487.60g/mol
Synonym C-3890; Z-Val-Val-Nle-DMK
Product Type Signal Transduction Reagent
Form Powder
InChI Key IIPZPLSBQVJCBO-UHFFFAOYNA-N
SMILES CCCCC(NC(=O)C(NC(=O)C(NC(=O)OCC1=CC=CC=C1)C(C)C)C(C)C)C(=O)C=[N+]=[N-]
IUPAC Name benzyl N-[1-({1-[(1-diazo-2-oxoheptan-3-yl)carbamoyl]-2-methylpropyl}carbamoyl)-2-methylpropyl]carbamate
Molecular Weight (g/mol) 487.60
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