missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organonitrogen Compounds
  6. Guanidines
  7. Zoniporide dihydrochloride, Tocris Bioscience™

Zoniporide dihydrochloride, Tocris Bioscience™

Product Code. 18023852
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective NHE1 inhibitor

Sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor that displays selectivity over other NHE isoforms (Ki values are 14, 2200 and 220000 nM for human NHE1, human NHE2 and rat NHE3 respectively). Inhibits NHE1 dependent 22Na+ uptake in vitro (IC50 = 14 nM) and provides cardioprotection from myocardial ischemic injury in vivo (EC50 = 0.25 nM). Also inhibits MMP2/9 activity and invasion in breast cancer cells.

Chemical Identifiers

CAS 241799-10-0
Molecular Formula C17H18Cl2N6O
Molecular Weight (g/mol) 393.272
InChI Key ARZNPJAGKWHEHT-UHFFFAOYSA-N
Synonym zoniporide dihydrochloride, 1-quinolin-5-yl-5-cyclopropyl-1h-pyrazole-4-carbonyl guanidine dihydrochloride
PubChem CID 22267855
IUPAC Name 5-cyclopropyl-N-(diaminomethylidene)-1-quinolin-5-ylpyrazole-4-carboxamide;dihydrochloride
SMILES C1CC1C2=C(C=NN2C3=CC=CC4=C3C=CC=N4)C(=O)N=C(N)N.Cl.Cl

Specifications

Quantity 10 mg
Formula Weight 393.27
Percent Purity >99%
Chemical Name or Material Zoniporide dihydrochloride
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.