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1 – 15 of 37 results
1

Tocris Bioscience™ MZ 1

(+)-JQ1 based Degrader (PROTAC™) that selectively degrades BRD4

3

Tocris Bioscience™ VH 298

High-affinity inhibitor of VHL

Content And Storage Store at -20°C
Target Proteins Ubiquitin Ligase (E3)
Product Type Inhibitor
For Use With (Application) Ubiquitin Ligase (E3) Inhibitors
Molecular Formula C27H33N5O4S
Formula Weight 523.65g/mol
4

Tocris Bioscience™ SR 9243

Selective LXR inverse agonist

Content And Storage Store at 4°C
CAS 1613028-81-1
Product Type Inhibitor
Solubility Soluble to 20mM in DMSO
Color White
For Use With (Application) Inhibits IL-1β
Molecular Formula C31H32BrNO4S2
Formula Weight 626.62g/mol
5

Tocris Bioscience™ NAV 2729

Selective ARF6 inhibitor

Content And Storage Store at 4°C
CAS 419547-11-8
Product Type Inhibitor
Solubility Soluble to 100mM in DMSO
Color Yellow
For Use With (Application) Blocks downstream signaling pathways
Molecular Formula C25H17ClN4O3
Formula Weight 456.88g/mol
7

Tocris Bioscience™ AZ 10397767

Potent CXCR2 antagonist

Content And Storage Store at -20°C
CAS 333742-63-5
Target Proteins Chemokine Receptor
Product Type Antagonist
For Use With (Application) Chemokine Receptor Antagonists
Molecular Formula C15H14ClFN4O2S2
Formula Weight 400.88g/mol
10

Tocris Bioscience™ ML 315 hydrochloride

Low molecular weight, organic compound that may help regulate biological process.

Content And Storage Store at -20°C
CAS 1440251-53-5
Target Proteins Cdc2-like Kinase
Product Type Inhibitor
For Use With (Application) Cdc2-like Kinase Inhibitors
Molecular Formula C18H13Cl2N3O2.HCl
Formula Weight 410.68g/mol
11

Tocris Bioscience™ B I09

IRE1 endonuclease inhibitor; cell permeable

Content And Storage Store at -20°C
CAS 1607803-67-7
Product Type Inhibitor
Solubility Soluble to 50mM in DMSO
Color Beige
For Use With (Application) Inhibits Rnase
Molecular Formula C16H17NO5
Formula Weight 303.31g/mol
12

Tocris Bioscience™ Arformoterol Tartrate

Low molecular weight, organic compound that may help regulate biological process.

Content And Storage Store at 4°C
CAS 200815-49-2
Target Proteins Adrenergic beta-2
Product Type Long-acting Agonist (LABA)
For Use With (Application) Adrenergic beta-2 Receptor Agonists
Molecular Formula C19H24N2O4.C4H6O6
Formula Weight 494.49g/mol
13

Tocris Bioscience™ BOP

Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs

Content And Storage Store at -20°C
CAS 1947348-42-6
Product Type Inhibitor
Solubility Soluble to 100mM in water and to 100mM in DMSO
Color White
Synonym N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt
For Use With (Application) Inhibits integrin
Molecular Formula C25H28N3O7SNa
Formula Weight 537.56
14

Tocris Bioscience™ FTY 720

Potent S1P receptor agonist; also immunosuppressant

Content And Storage Store at -20°C
CAS 162359-56-0
Target Proteins Sphingosine-1-phosphate Receptor
Product Type Agonist
Synonym Fingolimod, Gilenya
For Use With (Application) Sphingosine-1-phosphate Receptor Agonists
Molecular Formula C19H33NO2.HCl
Formula Weight 343.93g/mol