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Tocris Bioscience™ AZ 10397767
Potent CXCR2 antagonist
263.00 EUR - 1065.00 EUR
Specifications
| Product Type | Antagonist |
|---|---|
| Target Proteins | Chemokine Receptor |
| CAS | 333742-63-5 |
| Molecular Formula | C15H14ClFN4O2S2 |
| Formula Weight | 400.88g/mol |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18777686
|
Tocris Bioscience™
5872/10 |
10 mg |
263.00 EUR
10mg |
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|
18797936
|
Tocris Bioscience™
5872/50 |
50 mg |
1065.00 EUR
50mg |
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Description
Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.Specifications
| Antagonist | |
| 333742-63-5 | |
| 400.88g/mol | |
| Chemokine Receptor Antagonists |
| Chemokine Receptor | |
| C15H14ClFN4O2S2 | |
| Store at -20°C |
For Research Use Only
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