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Tocris Bioscience™ AZ 10397767

Potent CXCR2 antagonist

Brand: Tocris Bioscience™ 5872/10

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Product Code. 18777686

263.00 EUR / 10mg

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Description

AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.

Specifications

Product Type	Antagonist
CAS	333742-63-5
Formula Weight	400.88g/mol
For Use With (Application)	Chemokine Receptor Antagonists

Target Proteins	Chemokine Receptor
Molecular Formula	C₁₅H₁₄ClFN₄O₂S₂
Content And Storage	Store at -20°C
Quantity	10 mg

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Tocris Bioscience™ AZ 10397767

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