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2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, 98%, Thermo Scientific Chemicals Product Code.: 11383127
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2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, 98%, Thermo Scientific Chemicals

Product Code. 11383127
25 g
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Quantity:
5 g
25 g
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Product Code. 11383127

Brand: Thermo Scientific Alfa Aesar L13538.14

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Description

2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips.

Solubility
Soluble in acetonitrile, DMF, chloroform, dichlorormethane and acetonitrile.

Notes
Moisture sensitive, Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 105832-38-0
Molecular Formula C9H16BF4N3O3
Molecular Weight (g/mol) 301.05
MDL Number MFCD00077875
InChI Key YEBLHMRPZHNTEK-UHFFFAOYSA-N
Synonym tstu, o-n-succinimidyl-1,1,3,3-tetramethyluronium tetrafluoroborate, 2-2,5-dioxopyrrolidin-1-yl-1,1,3,3-tetramethylisouronium tetrafluoroborate, 2-succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, n,n,n',n'-tetramethyl-o-n-succinimidyl uronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyluronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl-uronium tetrafluoroborate, dimethylamino 2,5-dioxopyrrolidin-1-yl oxy methylidene dimethylazanium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl uronium bf4, pubchem12781Show MoreShow Less
PubChem CID 9857522
IUPAC Name [dimethylamino-(2,5-dioxopyrrolidin-1-yl)oxymethylidene]-dimethylazanium;tetrafluoroborate
SMILES F[B-](F)(F)F.CN(C)C(ON1C(=O)CCC1=O)=[N+](C)C

Specifications

Melting Point 195°C to 200°C
Quantity 25 g
Sensitivity Moisture sensitive
Solubility Information Soluble in acetonitrile,DMF,chloroform,dichlorormethane and acetonitrile.
Formula Weight 301.05
Percent Purity 98%
Chemical Name or Material 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate

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Lot Number Certificate Type Date Catalog Number
Lot Number10243834 Certificate TypeCertificate of Analysis Date13/10/2022 Catalog NumberL13538.14,L13538.06
Lot Number10157588 Certificate TypeCertificate of Analysis Date08/12/2021 Catalog NumberL13538.14,L13538.06
Lot Number10194022 Certificate TypeCertificate of Analysis Date08/12/2021 Catalog NumberL13538.14,L13538.06
Lot Number10237073 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberL13538.14,L13538.06
Lot NumberGBFA014829 Certificate TypeCertificate of Analysis Date06/12/2021 Catalog NumberL13538.14,L13538.06

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