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Tocris Bioscience™ A01

High affinity Smurf1 inhibitor; enhances BMP signaling

Brand: Tocris Bioscience™ 5397/50

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Product Code. 18767078

872.00 EUR / 50mg

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Description

A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM). Attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Potentiates BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells.

Specifications

Purity	>98%
Product Type	A01
Inhibitors	A01

Quantity	50 mg
Molecular Weight (g/mol)	512.93

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Tocris Bioscience™ A01

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