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Tocris Bioscience™ A01

High affinity Smurf1 inhibitor; enhances BMP signaling

228.00 EUR - 872.00 EUR

Specifications

Purity >98%
Product Type A01
Molecular Weight (g/mol) 512.93
Inhibitors A01
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18732459
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Tocris Bioscience™
5397/10
10 mg
228.00 EUR
10mg
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18767078
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Tocris Bioscience™
5397/50
50 mg
872.00 EUR
50mg
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Description

Description

High affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM). Attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Potentiates BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells.
Specifications

Specifications

>98%
A01
512.93
A01
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For Research Use Only

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