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  6. 18033872

Tocris Bioscience™ AC 1903

Selective TRPC5 blocker

Brand:  Tocris Bioscience™ 6766/5

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Product Code. 18033872

  • 97.00 EUR / 5mg

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Description

Description

AC 1903 is a selective TRPC5 blocker (IC50 = 13.6 μM). Also displays weak inhibition at TRPC4 (IC50 >100 μM) but not TRPC6. Exhibits no effect against a standard panel of profiling kinases. Blocks TRPC5 channel activity in glomeruli of proteinuric rats. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis (FSGS).
Specifications

Specifications

N-(2-Furanylmethyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine
5 mg
303.36
831234-13-0
C19H17N3O
98%
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