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Tocris Bioscience™ AC 1903

Selective TRPC5 blocker

97.00 EUR - 363.00 EUR

Specifications

Chemical Name or Material N-(2-Furanylmethyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine
CAS 831234-13-0
Molecular Formula C19H17N3O
Formula Weight 303.36
Purity 98%
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18719146
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Tocris Bioscience™
6766/25
25 mg
363.00 EUR
25mg
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18033872
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Tocris Bioscience™
6766/5
5 mg
97.00 EUR
5mg
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Description

Description

  • Selective TRPC5 blocker (IC50 = 13.6 μM)
  • Also displays weak inhibition at TRPC4 (IC50 >100 μM) but not TRPC6
  • Exhibits no effect against a standard panel of profiling kinases
  • Blocks TRPC5 channel activity in glomeruli of proteinuric rats
  • Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis (FSGS)
Specifications

Specifications

N-(2-Furanylmethyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine
C19H17N3O
98%
831234-13-0
303.36
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
Documents

Documents

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