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Tocris Bioscience™ AC 1903
Selective TRPC5 blocker
97.00 EUR - 363.00 EUR
Specifications
Chemical Name or Material | N-(2-Furanylmethyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine |
---|---|
CAS | 831234-13-0 |
Molecular Formula | C19H17N3O |
Formula Weight | 303.36 |
Purity | 98% |
Description
- Selective TRPC5 blocker (IC50 = 13.6 μM)
- Also displays weak inhibition at TRPC4 (IC50 >100 μM) but not TRPC6
- Exhibits no effect against a standard panel of profiling kinases
- Blocks TRPC5 channel activity in glomeruli of proteinuric rats
- Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis (FSGS)
Specifications
N-(2-Furanylmethyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine | |
C19H17N3O | |
98% |
831234-13-0 | |
303.36 |
Safety and Handling
Recommended Storage : Store at -20°C
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