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AMG 9810, Tocris Bioscience™

Product Code. 30001298
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and selective, competitive antagonist of TRPV1

Potent and selective, competitive vanilloid TRPV1 receptor antagonist (IC50 = 17 nM). Inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. Displays antihyperalgesic properties in a rat model of inflammatory pain.

Chemical Identifiers

CAS 545395-94-6
Molecular Formula C21H23NO3
Molecular Weight (g/mol) 337.419
InChI Key GZTFUVZVLYUPRG-IZZDOVSWSA-N
Synonym unii-182hij2d7f, 2e-3-4-tert-butylphenyl-n-2,3-dihydro-1,4-benzodioxin-6-yl prop-2-enamide, 2e-n-2,3-dihydro-1,4-benzodioxin-6-yl-3-4-1,1-dimethylethyl phenyl-2-propenamide, trans-cinnamide, d0xo2g, e-3-4-t-butylphenyl-n-2,3-dihydrobenzo b 1,4 dioxin-6-yl acrylamide, 3-4-t-butylphenyl-n-2,3-dihydrobenzo b 1,4 dioxin-6-yl acrylamide, amg hplc , powder, e-3-4-tert-butylphenyl-n-2,3-dihydro-1,4-benzodioxin-6-yl prop-2-enamide
PubChem CID 680502
IUPAC Name (E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enamide
SMILES CC(C)(C)C1=CC=C(C=C1)C=CC(=O)NC2=CC3=C(C=C2)OCCO3

Specifications

Quantity 10 mg
Formula Weight 337.42
Percent Purity >98%
Chemical Name or Material AMG 9810
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