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Human AMPK A2/B1/G1, GST Tag, His Tag Recombinant Protein

Human AMPK A2/B1/G1, GST Tag, His Tag Recombinant Protein

Brand:  Invitrogen PV4674

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Product Code. 10611864

  • 1052.00 EUR / Each

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Description

Description

AMP-activated protein kinase (AMPK) is a heterotrimeric complex that acts as a sensor of cellular energy levels. The signaling cascades initiated by activating AMPK are critical to regulating metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. An impairment in fuel metabolism that occurs in obesity is a factor leading to Type 2 diabetes. The insulin resistance associated with type 2 diabetes is most profound at the level of skeletal muscle, the primary site of glucose and fatty acid utilization. Activation of AMPK is of interest for the treatment of type 2 diabetes.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NP_0062243.2 I NP_006244.2 I NP_002724.1
91.4/ 57.8/ 41.7 kDa
AMPK A2/B1/G1
Human
GST Tag, His Tag
Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Dry Ice
GST (N-Terminal)⁄GST (N-Terminal)⁄His (N-Terminal)
Baculovirus
Recombinant, Full Length
Serine/Threonine Kinases
Kinase Assay
10 μg
CAMKL Kinase Family
Recombinant
Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Ser⁄Thr Kinases: CAMK Group
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate
AMPK (A2/B1/G1)
Kinases & Inhibitors
Liquid
Signal Transduction
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