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CD38 Monoclonal Antibody (6E12D), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515570

Product Code. 11365533

  • 528.00 EUR / 100µL

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Description

Description

MA5-15570 targets CD38 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15570 immunogen is purified recombinant fragment of human CD38 expressed in E. Coli. MA5-15570 detects CD38 which has a predicted molecular weight of approximately 34kDa.

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD38
Monoclonal
Conc. Not Determined
ascites with 0.03% sodium azide
P28907
CD38
Purified recombinant fragment of human CD38 expressed in E. Coli.
RUO
952
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Immunohistochemistry, Western Blot
6E12D
Unconjugated
CD38
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10
Mouse
100 μL
Primary
Human
Antibody
IgG1
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