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Invitrogen™ Human CDC42 BPG (MRCKG), GST Tag Recombinant Protein
Human CDC42 BPG (MRCKG), GST Tag Recombinant Protein
Brand: Invitrogen™ A32861
This item is not returnable.
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Description
CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.- Validated for use with the Z’-LYTE™ assay
- Available in multiple pack sizes for convenient use
Specifications
| NP_059995 | |
| 80.2 kDa | |
| Other Kinase Family | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Recombinant, Active, Catalytic |
| Kinase Assay | |
| 100 μg | |
| aa 1 - 475 | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Insect | |
| Liquid |