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Invitrogen™ Human CDC42 BPG (MRCKG), GST Tag Recombinant Protein

Human CDC42 BPG (MRCKG), GST Tag Recombinant Protein

Specifications

Accession Number NP_059995
For Use With (Application) Kinase Assay
Molecular Weight (g/mol) 80.2 kDa
KinaseFamily Other Kinase Family
Protein Length aa 1 - 475
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Products 3 Description

Description

CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.
  • Validated for use with the Z’-LYTE™ assay
  • Available in multiple pack sizes for convenient use
Specifications

Specifications

NP_059995
80.2 kDa
aa 1 - 475
Recombinant
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Recombinant, Active, Catalytic
Kinase Assay
Other Kinase Family
Human
GST Tag
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Liquid
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