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DIDS, Tocris Bioscience™

Name: DIDS, Tocris Bioscience&trade;
Brand: Tocris Bioscience

Product Code. 18004002

50 mg

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50 mg

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Product Code. 18004002

Brand: Tocris Bioscience 4523/50

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Description

Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

ClC-Ka chloride channel blocker (IC50 = 100 μM). Blocks the maxi chloride channel in apical membranes from human placenta. Displays antagonistic activity at TRPM4 and TRPC4 channels; potentiates agonist-induced TRPV1 currents (IC50 = 4.88 μM in rat DRG neurons). Inhibits RAD51 recombinase activity (KD = 2 μM).

Specifications

CAS	67483-13-0
Molecular Formula	C16H8N2Na2O6S4
Quantity	50 mg
Synonym	dids, unii-1vfrq7416a, disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulfonate, 4,4'-diisothiocyanato-2,2'-stilbenedisulfonic acid disodium salt, 4,4'-diisothiocyano-2,2'-stilbenedisulfonic acid, disodium salt, disodium 5-isothiocyanato-2-e-2-4-isothiocyanato-2-sulfonatophenyl ethenyl benzenesulfonate, spectrum1505164, 4 4'-diisothiocyanato-2 2'-stilbenedisu, disodium 4,4'-diisothiocyanatostilbene-2,2'-disulfonate, disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulfonate, e
InChI Key	GEPAYBXVXXBSKP-SEPHDYHBSA-L
SMILES	C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])C=CC2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+]
IUPAC Name	disodium;5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfonatophenyl)ethenyl]benzenesulfonate
Molecular Weight (g/mol)	498.468
PubChem CID	5702690
Formula Weight	498.48
Percent Purity	>95%
Chemical Name or Material	DIDS
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DIDS, Tocris Bioscience™

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