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Ethyl chloroformate, 97%, Thermo Scientific Chemicals
Description
Ethyl chloroformate is used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. It is also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. It is used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Ethyl chloroformate is used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. It is also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. It is used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography.
Solubility
Not miscible in water.
Notes
Protect from heat. Store away from moisture and oxidizing agents. Store under dry inert gas. Refrigerate. Incompatible with heat, moisture and oxidizing agents.

Specifications
Specifications
Melting Point | -81°C |
Density | 1.136 |
Boiling Point | 92°C to 93°C |
Flash Point | 10°C (50°F) |
Odor | Pungent |
Linear Formula | ClCO2CH2CH3 |
Refractive Index | 1.395 |
Quantity | 100 g |
UN Number | UN1182 |
Beilstein | 385653 |
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Safety and Handling



- Ethyl chloroformate
- Danger
- Acute toxicity Category 1
- Acute toxicity Category 3
- Serious eye damage/eye irritation Category 1
- Flammable liquid Category 2
- Skin corrosion/irritation Category 1 B
- H225-Highly flammable liquid and vapour.
- H301-Toxic if swallowed.
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H330-Fatal if inhaled.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : Ethyl chloroformate
RUO – Research Use Only
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