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Thermo Scientific™ GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells

GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.

Brand: Thermo Scientific™ K1716

Product Code. 10773734

16470.00 EUR / Each

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Estimated Shipment: 01-04-2025
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Description

GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ M3-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC₅₀ concentrations of Carbachol. In addition, GeneBLAzer™ M3-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The M3 receptor is localized in smooth muscle, exocrine glands, and the central nervous system. M3 has been implicated in autoimmune and neurological disorders.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

Specifications

Accession Number	NM_000740.2
Cell State	Dividing Cells
Detection Method	Fluorescence
Gene Symbol	M3
Population Status	Single Cell Clone Origin
Quantity	2 x 10⁶ Cells
Target Entry	M3
Cell Line	CHO-K1
Druggable Target	GPCR

Assay Entry	Cell-based beta lactamase reporter gene
Content And Storage	LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • GeneBLAzer™ M3-NFAT-bla CHO-K1 cells • GeneBLAzer™ M3-NFAT-bla CHO-K1 Assay Protocol • Certificate of Analysis The GeneBLAzer™ M3-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application)	FRET
Includes	M3-NFAT-bla CHO-K1 cells, M3-NFAT-bla CHO-K1 Assay Protocol, Certificate of Analysis
Product Line	GeneBLAzer™
Reporter Gene	BLA (Beta-Lactamase)
Type	Dividing Cells
System Type	GeneBLAzer™

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Lot Number

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Lot Number	Certificate Type	Date	Catalog Number
Lot Number893286	Certificate TypeCertificate of Analysis	Date16/04/2017	Catalog NumberK1716

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Thermo Scientific™ GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells

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