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Tocris Bioscience™ Hh-Ag1.5

Potent and high affinity Smo receptor agonist

Brand:  Tocris Bioscience™ 7807/5

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Product Code. 18758716

  • 713.00 EUR / 5mg

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Description

Description

Hh-Ag1.5 is a potent and high affinity Hedgehog (Hh) receptor agonist (EC50 = 1 nM; Ki values are 0.5 and 2.3 nM respectively, in a [3H]SAG-1.3 and [3H]Cyclopamine binding assay). It is used in protocols for the chemical reprogramming of mouse embryonic fibroblasts into neural stem cells. Also induces differentiation of hiPSCs into skin-derived precursor cells, spinal motor neurons and spinal sensory neurons.
Specifications

Specifications

3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide
5 mg
C28H26ClF2N3OS
612542-14-0
Smoothened
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