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Tocris Bioscience™ Hh-Ag1.5
Potent and high affinity Smo receptor agonist
229.00 EUR - 713.00 EUR
Specifications
| Chemical Name or Material | 3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide |
|---|---|
| CAS | 612542-14-0 |
| Target | Smoothened |
| Molecular Formula | C28H26ClF2N3OS |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18779976
|
Tocris Bioscience™
7807/1 |
1 mg |
229.00 EUR
1mg |
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|
18758716
|
Tocris Bioscience™
7807/5 |
5 mg |
713.00 EUR
5mg |
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Description
Hh-Ag1.5 is a potent and high affinity Hedgehog (Hh) receptor agonist (EC50 = 1 nM; Ki values are 0.5 and 2.3 nM respectively, in a [3H]SAG-1.3 and [3H]Cyclopamine binding assay). It is used in protocols for the chemical reprogramming of mouse embryonic fibroblasts into neural stem cells. Also induces differentiation of hiPSCs into skin-derived precursor cells, spinal motor neurons and spinal sensory neurons.Specifications
| 3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide | |
| 612542-14-0 | |
| Smoothened | |
| C28H26ClF2N3OS |
Safety and Handling
Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.