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Gibco™ Human GM-CSF Recombinant Protein, PeproTech®

Recombinant Protein

83.75 EUR - 3360.00 EUR

Specifications

Accession Number P04141
For Use With (Application) ELISA, Functional Assay, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 1437
Molecular Weight (g/mol) 14.6 kDa
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Products 7
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17850053
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Gibco™
300-03-100UG
100 μg
674.00 EUR
100µg
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17851803
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Gibco™
300-03-1MG
1 mg
3360.00 EUR
1mg
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17831823
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Gibco™
300-03-20UG
20 μg
203.00 EUR
20µg
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17871803
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Gibco™
300-03-250UG
250 μg
1180.00 EUR
250µg
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17830533
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Gibco™
300-03-500UG
500 μg
2010.00 EUR
500µg
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17861303
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Gibco™
300-03-50UG
50 μg
402.00 EUR
50µg
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17880033
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Gibco™
300-03-5UG
5 μg
83.75 EUR
5µg
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Description

Description

Recombinant Human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids, containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
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