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Gibco™ Human R-Spondin-3 Recombinant Protein, PeproTech®
Recombinant Protein
Brand: Gibco™ 120-44-20UG
188.10 EUR valid until 2025-05-31
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This item is not returnable.
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Description
Recombinant Human R-Spondin-3 is a 26.9 kDa protein consisting of 240 amino acid residues. Due to glycosylation, R-Spondin-3 migrates at an apparent molecular weight of approximately 37.0 kDa by SDS PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development.
Specifications
| Q9BXY4 | |
| protein with no preservative | |
| 26.9 kDa | |
| 20 μg | |
| RUO | |
| 2810459H04Rik; AW742308; Cabriolet; cristin 1; Cristin1; cristin-1; cysteine-rich and single thrombospondin domain-containing protein 1; hPWTSR; hRspo3; Nucleopondin; protein with TSP type-1 repeat; PWTSR; RGD1563246; Roof plate-specific spondin-3; Rspo3; R-spondin 3; R-spondin 3 homolog; R-spondin 3 homolog (Xenopus laevis); R-spondin 3-like protein; R-spondin-3; Thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain 2; thrombospondin, type I, domain containing 2; Thsd2; Unknown (protein for MGC:137973) | |
| RSPO3 | |
| Unconjugated | |
| MHPNVSQGCQ GGCATCSDYN GCLSCKPRLF FALERIGMKQ IGVCLSSCPS GYYGTRYPDI NKCTKCKADC DTCFNKNFCT KCKSGFYLHL GKCLDNCPEG LEANNHTMEC VSIVHCEVSE WNPWSPCTKK GKTCGFKRGT ETRVREIIQH PSAKGNLCPP TNETRKCTVQ RKKCQKGERG KKGRERKRKK PNKGESKEAI PDSKSLESSK EIPEQRENKQ QQKKRKVQDK QKSVSVSTVH | |
| CHO cells | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 84870 | |
| Human R-Spondin-3 | |
| CHO cells | |
| <1 EU/ μg | |
| RSPO3 | |
| R-Spondin-3 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 for this effect is 0.8 -2.0 ug/ml | |
| Recombinant | |
| -20°C | |
| Lyophilized |
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Product Title
Gibco™ Human R-Spondin-3 Recombinant Protein, PeproTech® > 20 μg; Unlabeled
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