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Proteintech HumanKine™ recombinant human IL-5 protein
HumanKine™ recombinant protein
137.00 EUR - 2994.00 EUR
Specifications
| Accession Number | P05113 |
|---|---|
| Formulation | 1 x PBS |
| Gene ID (Entrez) | 3567 |
| Molecular Weight (g/mol) | 35-38 kDa |
| Source | HEK293 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17640097
|
Proteintech
HZ-1324-1000UG |
1000 μg |
2994.00 EUR
1000µg |
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|
17650097
|
Proteintech
HZ-1324-100UG |
100 μg |
594.00 EUR
100µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
17660097
|
Proteintech
HZ-1324-10UG |
10 μg |
137.00 EUR
10µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
IL-5 is a 4-α-helix, pleiotropic cytokine that regulates the activities of B cells, eosinophils, and basophils. It is produced mostly by CD4+ T cells, eosinophils, and basophils, and signals through its specific receptor (IL-5R) on target cells to activate downstream JAK/STAT, Btk, and Ras/ERk pathways. Due to its pleiotropic effects, IL-5 plays a role in both innate and adaptive immune responses. It is a strong promoter of eosinophil differentiation, migration, maturation, and survival. Additionally, IL-5 is also capable of stimulating activated B cells to differentiate into antibody-secreting cells. Elevated IL-5 levels are strongly correlated with eosinophilia, which is a hallmark feature of allergy, asthma, and hypersensitivity (PMID: 21986312, 22174445, 19819937, 16895557)Specifications
| P05113 | |
| 3567 | |
| HEK293 | |
| <0.1 EU/μg | |
| Recombinant | |
| 0.2-0.9 ng/mL EC50 | |
| >95% |
| 1 x PBS | |
| 35-38 kDa | |
| Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.) | |
| Human | |
| Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA). | |
| Lyophilized |
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Product Title
Proteintech HumanKine™ recombinant human IL-5 protein