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  5. Thermo Scientific Chemicals L(-)-Proline, 99+%

Thermo Scientific Chemicals L(-)-Proline, 99+%

Product Code. 10081810
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Quantity:
5 g
25 g
100 g
500 g
Packaging:
Glass Bottle
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Description

L-Proline CAS 147-85-3, (synonym: (S)-Pyrrolidine-2-carboxylic acid) is a nonessential amino acid and building block of proteins that has applications such as acting as catalyst in chemical reactions.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• L-Proline is an amino acid that is found as a component of various proteins.

Application
• L-Proline is used as asymmetric catalyst in organic synthesis and asymmetric aldol cyclization
• It is also used along with ninhydrin in chromatography
• It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes
• It is used in pharmaceutical and biotechnological applications due to its osmoprotactant property
• It is precursor of hydroxyproline in collage and involved in proper functioning of joint and tendons

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 147-85-3
Molecular Formula C5H9NO2
Molecular Weight (g/mol) 115.13
MDL Number MFCD00064318
InChI Key ONIBWKKTOPOVIA-UHFFFAOYNA-N
Synonym l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh
PubChem CID 145742
ChEBI CHEBI:17203
SMILES OC(=O)C1CCCN1

Specifications

Ammonium 200ppm max.
Arsenic (As) 1ppm max.
pH 5.5 to 7 (2.5% soln. at 25°C)
Color White
Chlorine (Cl) 200ppm max.
Heavy Metals (as Pb) 10ppm max.
Assay Percent Range 99+%
Infrared Spectrum Authentic
Iron (Fe) 10ppm max.
Beilstein 22, 2
Fieser 06,492; 08,421; 09,393; 10,331; 11,446; 13,292
Loss on Drying 0.3% max. (105°C, 3 hrs)
Merck Index 15, 7895
Other Amino Acids 0.5% max. (TLC)
Packaging Glass Bottle
IUPAC Name (2S)-pyrrolidine-2-carboxylic acid
Specific Rotation -84.5° to -86.8° (20°C, 589nm) (c=4, H2O)
Sulfate 200ppm max.
Formula Weight 115.13
Transmittance 95% min. (c=10, H2O, 430nm) 1cm cell
Percent Purity 99.0 to 101.0%
Sulfated Ash 0.1% max.
Density 1.3500g/mL
Specific Rotation Condition − 85.50 (20.00°C c=4,H2O)
Quantity 25 g
Physical Form Crystalline Powder or Crystals
Chemical Name or Material L(-)-Proline
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