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M3258, MedChemExpress
MedChemExpress M3258 is an orally bioavailable, potent, reversible and highly selective immunoproteasome subunit LMP7 (β5i) inhibitor.
544.05 EUR - 823.50 EUR
Specifications
| Chemical Name or Material | M3258 |
|---|---|
| CAS | 2285330-15-4 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C17H20BNO5 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16484528
|
Medchem Express
HY-111790 |
10 mg |
823.50 EUR
10mg |
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|
16417247
|
Medchem Express
HY-111790 |
5 mg |
544.05 EUR
5mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
M3258 exerts high biochemical (IC50=3.6 nM) and cellular (IC50=3.4 nM) potency against the LMP7 subunit. M3258 shows strong antitumor efficacy in multiple myeloma xenograft models. M3258 leads to a significant and prolonged suppression of tumor LMP7 activity and ubiquitinated protein turnover and the induction of apoptosis in multiple myeloma cells.Specifications
| M3258 | |
| White | |
| C17H20BNO5 | |
| O=C(N[C@@H](CC1=COC2=C1C=CC=C2)B(O)O)[C@H]3[C@@H]4CC[C@@H](O4)C3 | |
| 329.16 | |
| Research | |
| Cancer-Kinase/protease |
| 2285330-15-4 | |
| Research | |
| DMSO : 250 mg/mL (759.51 mM; Need ultrasonic) | |
| 329.16 | |
| 98.0% | |
| Solid |
Safety and Handling
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only
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