Learn More
Cytiva™ MabSelect™ VL Protein L Resin
Shop All Cytiva ProductsDescription
MabSelect™ VL resin with a redesigned protein L ligand for high binding capacity and improved alkaline stability. For affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
- High dynamic binding capacity protein L resin for efficient capture of antibody Fabs, bispecifics, and variants containing a kappa light chain
- Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
- Provides good resolution for product-related impurities in the capture of bispecific antibodies
As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.
Specifications
Specifications
| Bed Volume | 25 mL |
| Flow Rate | 300 cm/hr. |
| Ligand Type | Alkaline Stabilized Protein L-derived (E. coli) |
| pH Range | 2 to 10 |
| Particle Size | 60 μm |
| Content And Storage | 2°C to 8°C, 20% Ethanol |
| For Use With (Application) | Antibody Affinity Chromatography |
| Matrix | VL Protein L Resin |
Safety and Handling
- MabSelect VL, 25 ml
- Warning
- Flammable liquid Category 3
- H226-Flammable liquid and vapour.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
- MIXTURE LIST-Contains : ethanol
- UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.
Your input is important to us. Please complete this form to provide feedback related to the content on this product.