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Tocris Bioscience™ NVP ADW 742

ATP-competitive inhibitor of IGF1R

173.00 EUR - 694.00 EUR

Specifications

Purity >99%
Product Type NVP ADW 742
Molecular Weight (g/mol) 453.58
Inhibitors NVP ADW 742
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18753968
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Tocris Bioscience™
5247/10
10 mg
173.00 EUR
10mg
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18743158
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Tocris Bioscience™
5247/50
50 mg
694.00 EUR
50mg
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Description

Description

ATP-competitive inhibitor of IGF1R (IC50 in the range of 0.1-0.2 μM). Also inhibits c-Kit kinase activity (IC50 in the range of 3-5 μM). Exhibits a synergistic effect with Imatinib, enhancing the sensitivity of multiple small cell lung cancer cell lines to the chemotherapeutics etoposide (Cat. No. 1226) and carboplatin (Cat. No. 2626).
Specifications

Specifications

>99%
NVP ADW 742
453.58
NVP ADW 742
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