missing translation for 'onlineSavingsMsg'
Learn More
Learn More
OAS3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA559539
This item is not returnable.
View return policy
Description
Immunogen sequence: TWDLGNGAAW HWDLLAQEAA SCYDHPCFLR GMGDPVQSWK GPGLPRAGCS GLGHPIQLDP NQKTPENSKS LNAVYPRAGS KPPSCP Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 27%.
OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
Specifications
| OAS3 | |
| Polyclonal | |
| Unconjugated | |
| OAS3 | |
| (2-5')oligo(A) synthase 3; (2-5')oligo(A) synthetase 3; 2',5'-oligoadenylate synthetase-like 10; 2'-5' oligoadenylate synthetase 3; 2'-5' oligoadenylate synthetase-like 10; 2-5A synthase 3; 2-5A synthetase 3; 2'-5'-oligoadenylate synthase 3; 2'-5'-oligoadenylate synthetase 3; 2'-5'-oligoadenylate synthetase 3, 100kDa; 2'-5'oligoadenylate synthetase p100; Oas3; oasl10; P/OKcl.4; p100; p100 OAS; p100OAS | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4940 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry, Western Blot | |
| 0.4 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9Y6K5 | |
| OAS3 | |
| Recombinant protein corresponding to Human OAS3 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
OAS3 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
Research Use Only
Spot an opportunity for improvement?Share a Content Correction
