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PFKFB1/PFKFB4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA5104524
This item is not returnable.
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Description
Antibody detects endogenous levels of total PFKFB1/4.
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
Specifications
| PFKFB1/PFKFB4 | |
| Polyclonal | |
| Unconjugated | |
| Pfkfb1 | |
| 6PF-2-K/Fru-2,6-P2ase 1; 6PF-2-K/Fru-2,6-P2ase 4; 6PF-2-K/Fru-2,6-P2ase liver isozyme; 6PF-2-K/Fru-2,6-P2ase testis-type isozyme; 6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4; bifunctional enzyme with kinase and biphosphatase activities; C230090D14; F6PK; Fructose-2,6-bisphosphatase; fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase; HL2K; PFK/FBPase 1; PFK/FBPase 4; PFK-2/FBPase-2 gene A; Pfkfb01; Pfkfb1; Pfkfb4; PFRX | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 18639, 24638, 270198, 5207, 5210, 54283 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P07953, P16118, P25114, P70266, Q16877, Q6DTY7 | |
| Pfkfb1, Pfkfb4 | |
| A synthesized peptide derived from human PFKFB1(Accession P16118), corresponding to amino acid residues I329-I379. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Product Title
PFKFB1/PFKFB4 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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