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Phenyl chloroformate, 99%, Thermo Scientific Chemicals
Description
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.
Solubility
Miscible with N,N-dimethylformamide.
Notes
Store in cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with bases, alcohols and amines. Hydrolyses in water.
Specifications
Specifications
Melting Point | -38°C |
Density | 1.246 |
Boiling Point | 188°C to 189°C |
Flash Point | 76°C (169°F) |
Refractive Index | 1.511 |
Quantity | 100 g |
UN Number | UN2746 |
Beilstein | 606778 |
Sensitivity | Moisture sensitive |
Solubility Information | Miscible with N,N-dimethylformamide. |
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Certificates
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
Lot Number | Certificate Type | Date | Catalog Number |
---|---|---|---|
Y09E059 | Certificate of Analysis | 22/11/2021 | A12618.22,A12618.30,A12618.36 |
10164416 | Certificate of Analysis | 22/11/2021 | A12618.22,A12618.30,A12618.36 |
10211243 | Certificate of Analysis | 22/11/2021 | A12618.22,A12618.30,A12618.36 |
P18G017 | Certificate of Analysis | 22/11/2021 | A12618.22,A12618.30,A12618.36 |
10218857 | Certificate of Analysis | 22/11/2021 | A12618.22,A12618.30,A12618.36 |
Safety and Handling
- Phenyl chloroformate
- Danger
- Acute toxicity Category 2
- Acute toxicity Category 4
- LONG-TERM AQUATIC HAZARD Chronic 3
- Serious eye damage/eye irritation Category 1
- Substances and mixtures corrosive to metals Category 1
- Skin corrosion/irritation Category 1 C
- Specific target organ toxicity Category 3
- H290-May be corrosive to metals.
- H302-Harmful if swallowed.
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H330-Fatal if inhaled.
- H335-May cause respiratory irritation.
- H412-Harmful to aquatic life with long lasting effects.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : Phenyl chloroformate
RUO – Research Use Only
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