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Phospho-PRC1 (Thr470) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA5106103
This item is not returnable.
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Description
Antibody detects endogenous levels of PRC1 only when phosphorylated at Thr470.
This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly.
Specifications
| Phospho-PRC1 (Thr470) | |
| Polyclonal | |
| Unconjugated | |
| PRC1 | |
| anaphase spindle elongation 1 homolog; ASE1; carboxypeptidase C PRC1; Carboxypeptidase Y; Carboxypeptidase YSCY; CPD-Y; CPY1; D7Ertd348e; LBC1; MGC1671; MGC3669; prc1; protein regulating cytokinesis 1; protein regulator of cytokinesis 1; YMR297W | |
| Rabbit | |
| sequential chromatography | |
| RUO | |
| 233406, 9055 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O43663, Q99K43 | |
| PRC1 | |
| A synthesized peptide derived from human PRC1(Accession O43663), corresponding to amino acid residues around phosphorylated Thr470. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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Product Title
Phospho-PRC1 (Thr470) Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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