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PQ 401, Tocris Bioscience™

Product Code. 18045382
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

IGF1R inhibitor

Insulin-like growth factor receptor (IGF1R) inhibitor. Suppresses IGF-stimulated IGF-IR autophosphorylation with an IC50 value of 12 μM. Inhibits growth of MCF-7 breast cancer cells in vitro and in vivo.

Chemical Identifiers

CAS 196868-63-0
Molecular Formula C18H16ClN3O2
Molecular Weight (g/mol) 341.80
MDL Number MFCD00160558
InChI Key YBLWOZUPHDKFOT-UHFFFAOYSA-N
Synonym igf-1r inhibitor ii, 1-5-chloro-2-methoxyphenyl-3-2-methylquinolin-4-yl urea, unii-2n3lv83s8j, n-5-chloro-2-methoxyphenyl-n'-2-methyl-4-quinolinyl urea, n-2-methoxy-5-chlorophenyl-n′-2-methylquinolin-4-yl-urea, d0b4su, urea, n-5-chloro-2-methoxyphenyl-n'-2-methyl-4-quinolinyl, pq hplc , powder, 3-5-chloro-2-methoxyphenyl-1-2-methylquinolin-4-yl urea, n-2-methoxy-5-chlorophenyl-n'-2-methylquinolin-4-yl-urea
PubChem CID 9549305
IUPAC Name 1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
SMILES COC1=C(NC(=O)NC2=C3C=CC=CC3=NC(C)=C2)C=C(Cl)C=C1

Specifications

Quantity 10 mg
Formula Weight 341.79
Percent Purity >99%
Chemical Name or Material PQ 401
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