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RASSF1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA5102383
This item is not returnable.
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Description
Antibody detects endogenous levels of total RASSF1.
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Specifications
| RASSF1 | |
| Polyclonal | |
| Unconjugated | |
| RASSF1 | |
| 123F protein; 123F2; AA536941; AU044980; cardiac-specific ras association domain family 1 protein; NORE2A; pancreas-specific ras association domain family 1 protein; protein 123F2; Ras association (RalGDS/AF-6) domain family 1; Ras association (RalGDS/AF-6) domain family member 1; Ras association domain family 1; Ras association domain family member 1; ras association domain-containing protein 1; Rassf1; Rassf1A; RASSF1A tumor suppressor; Rassf1B; Rassf1C; RDA32; REH3P21; tumor suppressor protein RDA32; wu:fc17f02; WUGSC:H_LUCA12.5; zgc:112224; zgc:92505; zgc:92505 protein | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 11186, 363140, 56289 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q99MK9, Q9NS23 | |
| RASSF1 | |
| A synthesized peptide derived from human RASSF1(Accession Q9NS23), corresponding to amino acid residues G162-K212. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Product Title
RASSF1 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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