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SPDP, MedChemExpress

MedChemExpress SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).

Brand:  Medchem Express HY-100216

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Product Code. 16494256

  • 368.55 EUR / 100mg

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Description

Description

SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
Specifications

Specifications

SPDP
White
C12H12N2O4S2
SPDP Crosslinker
O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2
312.36
Research
68181-17-9
Research
100 mg
DMSO : 155 mg/mL (496.22 mM; Need ultrasonic)
312.36
97.0%
Solid
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