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TNFSF4 Monoclonal Antibody (OTI5D8), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA806677
This item is not returnable.
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Description
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predomitly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.Specifications
| TNFSF4 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P23510 | |
| TNFSF4 | |
| Full length human recombit protein of human TNFSF4 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI5D8 | |
| Unconjugated | |
| TNFSF4 | |
| CD134L, CD252, GP34, OX-40L, OX4OL, TNLG2B, TXGP1 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 7292 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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Product Title
TNFSF4 Monoclonal Antibody (OTI5D8), TrueMAB™, OriGene
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