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  7. VU 0357017 hydrochloride, Tocris Bioscience™

VU 0357017 hydrochloride, Tocris Bioscience™

Product Code. 18095192
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Quantity:
10 mg
50 mg
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Description

Positive allosteric modulator of M1 receptors

Positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM). Displays no activity at M2-M5 at concentrations up to 30 μM. Potentiates NMDA receptor currents in hippocampal neurons; activity reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant.

Chemical Identifiers

CAS 1135242-13-5
Molecular Formula C18H28ClN3O3
Molecular Weight (g/mol) 369.89
InChI Key XKJQVUIXSBOCPP-UHFFFAOYSA-N
Synonym vu 0357017 hydrochloride, vu0357017 hydrochloride, ethyl 4-2-2-methylbenzamido ethylamino piperidine-1-carboxylate hydrochloride, 4-2-2-methylbenzoyl amino ethyl amino-1-piperidinecarboxylic acid ethyl ester hydrochloride, ml071 hydrochloride, vu0357017 monohydrochloride, cid, hcl, vu0357017 monohydrochloride hplc
PubChem CID 25010775
IUPAC Name ethyl 4-[2-[(2-methylbenzoyl)amino]ethylamino]piperidine-1-carboxylate;hydrochloride
SMILES CCOC(=O)N1CCC(CC1)NCCNC(=O)C2=CC=CC=C2C.Cl

Specifications

Quantity 10 mg
Formula Weight 369.89
Percent Purity >98%
Chemical Name or Material VU 0357017 hydrochloride
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