Phenylacetic acids

1 – 13 of 13 results

RGX-104, MedChemExpress

MedChemExpress RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	596.08
Color	White
Physical Form	Solid
Chemical Name or Material	RGX-104
Grade	Research
SMILES	O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4=CC=CC=C4)C)=C1
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.35%
CAS	610318-54-2
Solubility Information	DMSO : 100 mg/mL (167.76 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula	C₃₄H₃₃ClF₃NO₃
Formula Weight	596.08

RGX-104 hydrochloride, MedChemExpress

MedChemExpress RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	632.54
Color	White
Physical Form	Solid
Chemical Name or Material	RGX-104 hydrochloride
Grade	Research
SMILES	O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4=CC=CC=C4)C)=C1.Cl
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.14%
CAS	610318-03-1
Solubility Information	DMSO : 150 mg/mL (237.14 mM; ultrasonic and warming and heat to 60°C)
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₃₄H₃₄Cl₂F₃NO₃
Formula Weight	632.54

MedChemExpress Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	296.15
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Diclofenac
Grade	Research
SMILES	O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.91%
CAS	15307-86-5
Solubility Information	DMSO : ≥ 3.5 mg/mL (11.82 mM)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₄H₁₁Cl₂NO₂
Formula Weight	296.15

AM211, MedChemExpress

MedChemExpress AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	500.51
Color	White
Physical Form	Solid
Chemical Name or Material	AM211
Grade	Research
SMILES	O=C(O)CC1=CC(C2=CC=C(C(F)(F)F)C=C2CN(CC)C(NCC3=CC=CC=C3)=O)=C(OC)C=C1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.11%
CAS	1175526-27-8
Solubility Information	DMSO : ≥ 125 mg/mL (249.75 mM)
Synonym	AM211 free acid
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₇F₃N₂O₄
Formula Weight	500.51

ONO-7300243, MedChemExpress

MedChemExpress ONO-7300243 is a novel, potent lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 μM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	461.55
Color	White
Physical Form	Solid
Chemical Name or Material	ONO-7300243
Grade	Research
SMILES	O=C(O)CC1=CC=C(CN(C(C2=CC(OC)=C(C)C(OC)=C2)=O)CCCC3=CC=CC=C3)C=C1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.14%
CAS	638132-34-0
Solubility Information	DMSO : 100 mg/mL (216.66 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₈H₃₁NO₅
Formula Weight	461.55

Olopatadine hydrochloride, MedChemExpress

MedChemExpress Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	373.87
Color	White
Physical Form	Solid
Chemical Name or Material	Olopatadine hydrochloride
Grade	Research
SMILES	O=C(O)CC1=CC=C(C/2=C1)OCC3=CC=CC=C3C2=C\CCN(C)C.Cl
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.97%
CAS	140462-76-6
Solubility Information	DMSO : 50 mg/mL (133.74 mM; Need ultrasonic) ∣H2O : 6.67 mg/mL (17.84 mM; Need ultrasonic)
Health Hazard 1	H301∣H400
Synonym	ALO4943A KW4679
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₁H₂₄ClNO₃
Formula Weight	373.87

AM966, MedChemExpress

MedChemExpress AM966 is a high affinity, selective, oral LPA1-antagonist, inhibits LPA-stimulated intracellular calcium release (IC50=17 nM).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	490.93
Color	Off-White
Physical Form	Solid
Chemical Name or Material	AM966
Grade	Research
SMILES	O=C(O)CC1=CC=C(C2=CC=C(C3=C(NC(O[C@@H](C4=CC=CC=C4Cl)C)=O)C(C)=NO3)C=C2)C=C1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.64%
CAS	1228690-19-4
Solubility Information	DMSO : 100 mg/mL (203.70 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₃ClN₂O₅
Formula Weight	490.93

GW3965 hydrochloride, MedChemExpress

MedChemExpress GW3965 hydrochloride is a potent and selective liver X receptor (LXR) agonist with EC50s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	618.51
Color	White
Physical Form	Solid
Chemical Name or Material	GW3965 hydrochloride
Grade	Research
SMILES	ClC1=C(C(F)(F)F)C=CC=C1CN(CC(C2=CC=CC=C2)C3=CC=CC=C3)CCCOC4=CC(CC(O)=O)=CC=C4.[H]Cl
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.13%
CAS	405911-17-3
Solubility Information	DMSO : 100 mg/mL (161.68 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Health Hazard 1	H302∣H318∣H413
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₃₃H₃₂Cl₂F₃NO₃
Formula Weight	618.51

AM095 free acid, MedChemExpress

MedChemExpress AM095 (free acid) is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	456.49
Color	Off-White
Physical Form	Solid
Chemical Name or Material	AM095 free acid
Grade	Research
SMILES	O=C(O)CC1=CC=C(C2=CC=C(C3=C(NC(O[C@@H](C4=CC=CC=C4)C)=O)C(C)=NO3)C=C2)C=C1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.07%
CAS	1228690-36-5
Solubility Information	DMSO : 67.3 mg/mL (147.43 mM; Need ultrasonic and warming)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₄N₂O₅
Formula Weight	456.49

Evocalcet, MedChemExpress

MedChemExpress Evocalcet has an activating effect on calcium sensing receptor (CaSR) extracted from patent WO 2017061621 A1, compound A.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	374.48
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Evocalcet
Grade	Research
SMILES	O=C(O)CC1=CC=C(N2C[C@@H](N[C@@H](C3=C4C=CC=CC4=CC=C3)C)CC2)C=C1
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	99.05%
CAS	870964-67-3
Solubility Information	DMSO : 30 mg/mL (80.11 mM; Need ultrasonic and warming)
Synonym	KHK7580
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₆N₂O₂
Formula Weight	374.48

Felbinac, MedChemExpress

MedChemExpress Felbinac is a potent non-steroidal anti-inflammatory agent, used to treat muscle inflammation and arthritis.

Pricing and Availability

Diclofenac diethylamine, MedChemExpress

MedChemExpress Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	369.29
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Diclofenac diethylamine
Grade	Research
SMILES	O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl.CCNCC
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.55%
CAS	78213-16-8
Solubility Information	DMSO : 150 mg/mL (406.18 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₁₈H₂₂Cl₂N₂O₂
Formula Weight	369.29

TES-1025, MedChemExpress

MedChemExpress TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	383.44
Color	Yellow
Physical Form	Solid
Chemical Name or Material	TES-1025
Grade	Research
SMILES	O=C1C(C#N)=C(C2=CC=CS2)N=C(SCC3=CC=CC(CC(O)=O)=C3)N1
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	95.11%
CAS	1883602-21-8
Solubility Information	DMSO : 100 mg/mL (260.80 mM; Need warming)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₈H₁₃N₃O₃S₂
Formula Weight	383.44

Phenylacetic acids

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