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Tocris Bioscience™ AZD 7762 hydrochloride

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2

204.00 EUR - 795.00 EUR

Specifications

Purity >98%
Product Type AZD 7762 hydrochloride
Molecular Weight (g/mol) 398.88
Inhibitors AZD 7762 hydrochloride
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18791548
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Tocris Bioscience™
5199/10
10 mg
204.00 EUR
10mg
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18786228
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Tocris Bioscience™
5199/50
50 mg
795.00 EUR
50mg
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Description

Description

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2 (IC50 vales are 5 nM for both kinases); displays at least >10 fold selectivity over a panel of 164 kinases. Potentiates cytotoxicity of DNA-damaging agents. Active in vivo. Also improves efficiency of CRISPR-Cpf1-mediated genome editing in hPSC lines (2.7-fold at 1 μM).
Specifications

Specifications

>98%
AZD 7762 hydrochloride
398.88
AZD 7762 hydrochloride
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