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Specifications
| Cell Type | Stem Cells |
|---|---|
| Classification | Xeno-free |
| Culture Type | Stem Cell (Human, iPS - Induced Pluripotent Stem, Embryonic) |
| Product Type | Extracellular Matrix |
| pH | 6 to 8 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15481044
|
Gibco™
A29249 |
1 mg |
726.00 EUR
100µg |
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|
15461945
|
Gibco™
A29248 |
100μg |
92.00 EUR
100µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Recombinant human Laminin 521 (rhLaminin-521) is a recombinant human protein that provides a defined surface for feeder-free culture of human pluripotent stem cells (PSCs). When used with Essential 8™ Medium, rhLaminin-521 has been proven to promote cellular survival under stressful conditions in the absence of small molecule inhibitors. rhLaminin-521 has been shown to support PSC growth for >20 passages without any signs of karyotypic abnormalities and to maintain the ability of PSCs to differentiate into all three germ line lineages. rhLaminin-521 also provides optimum reprogramming efficiency of human somatic cells as well as human pluripotent stem cell survival during feeder-dependent to feeder-free transitions when used in conjunction with Essential 8 Medium. For a kit that combines the medium and substrate, see the Essential 8™ Adaptation Kit.rhLaminin-521 is:
Trouble-free transition
When used with Essential 8 Medium, rhLaminin-521 provides a robust culture matrix that supports pluripotent stem cell adherence and expansion during the transition from feeder-dependent culture systems.
Efficient reprogramming
rhLaminin-521 has been shown to increase the number of colonies obtained during reprogramming of human fibroblasts, which can be important for in vitro disease modeling.
Confident expansion
rhLaminin-521 is expressed in blastocysts and therefore provides an environment mimicking the human stem cell niche.
Easy scale-up
rhLaminin-521 promotes stable pluripotent stem cell maintenance as single cells in the absence of ROCK inhibitors.
Spécification
| Stem Cells | |
| Stem Cell (Human, iPS - Induced Pluripotent Stem, Embryonic) | |
| 6 to 8 | |
| Dry Ice |
| Xeno-free | |
| Extracellular Matrix | |
| hESC-Qualified | |
| Xeno-Free |
For Research Use Only. Not for use in diagnostic procedures.
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