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Glutathione Reduced, Cell Culture Reagent, ≥98%, MP Biomedicals™ Product Code.: 11455202
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Glutathione Reduced, Cell Culture Reagent, ≥98%, MP Biomedicals™

Product Code. 11455202 Shop All MP Biomedicals Products
25 g
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Product Code. 11455202

Brand: MP Biomedicals 0219467925

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Description

Glutathione Reduced, Cell Culture Reagent, ≥98% is used for protein purification and elutes GST-tagged protein from glutathione agarose.

  • Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells.
  • It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
  • Glutathione is an endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst.
  • Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center.
  • Glutathione also forms disulfide bonds with cysteine residues in proteins.
  • Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
  • Typical Working Concentration: May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 70-18-8
Molecular Formula C10H17N3O6S
Molecular Weight (g/mol) 307.321
MDL Number MFCD00065939
InChI Key RWSXRVCMGQZWBV-WDSKDSINSA-N
Synonym glutathione, l-glutathione, glutathion, glutathione-sh, glutinal, isethion, tathion, reduced glutathione, deltathione, neuthion
PubChem CID 124886
ChEBI CHEBI:16856
IUPAC Name (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
SMILES C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N

Specifications

Melting Point 195°C
Color White
Assay Percent Range >98%
Quantity 25 g
Solubility Information 292.5 mg/mL
Formula Weight 307.32
Percent Purity ≥98%
Grade Cell Culture
Physical Form Powder
Chemical Name or Material Glutathione Reduced, Cell Culture Reagent

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