Test
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells.
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
GeneBLAzer™ H2-CRE-bla HEK293T cells contain the human Histamine Receptor 2 (H2) stably integrated into the CellSensor™ CRE-bla HEK293T cell line.
Tango™ HTR1A-bla U2OS cells contain the human Serotonin Type 1a receptor (HTR1A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
The CellSensor™ CRE HEK 293T DA (Division Arrested) cells contains a beta-lactamase (bla) reporter gene under control of a cAMP response element (CRE) stably integrated into HEK293T cells.
GeneBLAzer MCHR2-NFAT-bla CHO-K1 cells contain the human melanin-concentrating hormone receptor 2 (GPR145) stably integrated into the CellSensor NFAT-bla CHO-K1 parental cell line.
The Tango™ EDG1-bla U2OS cells contain the human Endothelial Differentiation, Sphingolipid G-protein-coupled Receptor, 1 (EDG1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Tango™ GPR39-bla U2OS cells contain the orphan human G-protein Coupled Receptor 39 (GPR39) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
The CellSensor™ NFAT CHO-K1 DA (Division Arrested) cells contain a beta-lactamase (bla) reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into CHO-K1 cells.
The GeneBLAzer™ NPSR1-B-NFAT-bla CHO-K1 cells contain the human Neuropeptide S Receptor 1-Isoform B (NPSR1-B), (Accession # NP_997056) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
GeneBLAzer™ P2RY4-NFAT-bla CHO-K1 cells contain the human Purinergic Receptor P2Y4 (P2RY4), stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
LXR alpha-UAS-bla HEK 293T 293 cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-alpha(LXR alpha) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.